https://www.ceesdekker.net Secrets
https://www.ceesdekker.net Secrets
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Nanotechnology offers a range of options to lead to biology. Listed here I'll current illustrations where by nanofabrication – the ability to make confined structures with Proportions at will – is used to examine the biophysics of one molecules and cells. I'll existing some illustrations from our lab:
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Back in 1991, Sumio Iijima of the NEC Corporation had reported the synthesis of carbon nanotubes. Band structure calculations recommended that these nanotubes could exhibit metallic band conduction. This would be a substantial advantage more than the conducting polymers we had explored, which were, actually, disordered semiconductors providing merely variable-variety hopping conductivity.
Considering the fact that 2000, Dekker has shifted the primary emphasis of his operate towards biophysics exactly where he experiments the Qualities of solitary biomolecules and cells utilizing the instruments of nanotechnology. This change of area was driven by his fascination for that exceptional operating of Organic molecular buildings, as well as from the prolonged-expression standpoint that many fascinating discoveries could be predicted During this field.[5] Present lines of study in his biophysics group are inside the regions of:[6]
That could be a desire of mine and we set to work which has a tasty dose of naivety. This is often something that will probably produce breathtaking brings about the lengthier expression, but that doesn't matter. You should not only want to operate over the queries of tomorrow, and also over the concerns on the working day after tomorrow.’
Cornelis (Cees) Dekker (Haren, seven april 1959) is een Nederlandse natuurkundige en universiteitshoogleraar verbonden aan de Technische Universiteit Delft. Van 2010 tot en satisfied 2018 was hij tevens directeur van het Kavli Institute of Nanoscience in Delft. Zijn vakgebied is de moleculaire biofysica; hierbij beweegt hij zich op het grensvlak van de natuurkunde en de biologie waarbij hij gebruikmaakt van de zogeheten nanotechnologie, de technieken om aan enkele atomen en moleculen te kunnen meten.
We shape bacteria into sorts that deviate from their purely natural phenotype. Specially, I will show our power to condition Dwell E. coli germs into novel shapes which include rectangles, squares, triangles and circles.
Atomic power microscopy demonstrates that vaccinia topoisomerase IB generates filaments on DNA in a cooperative trend
2003, demonstrated the initial biosensors produced from a carbon nanotube; solved the framework and mechanism of DNA repair proteins; and discovery of a completely new system for fabricating stable-condition nanopores for DNA translocation
Very amazing, but that wasn’t truly wherever my interest lay. I planned to pioneer And that i had the feeling which was now not feasible, since the most appealing fundamental insights had previously been uncovered. But my industry experienced created quite a few exciting new resources to measure ceesdekker.net particular person molecules. I made a decision that I desired to apply this to biology, to take a look at it from the Actual physical viewpoint.’
Case in point (four) of bending configurations in 3D simulations of DNA rods on nanopores. A part of the membrane is shown in gray, the rim on the pore is highlighted in crimson, as well as a 3D rendering from the movement on the DNA rod is shown.
Cees Dekker is Distinguished College Professor at TU Delft. Experienced for a physicist, he pioneered nanotechnology with lots of discoveries on carbon nanotubes during the nineteen nineties. Considering the fact that 2000, he moved to one-molecule biophysics and nanobiology. His present-day research focuses on (i) nanopores for protein sequencing; (ii) chromosome composition, specifically SMC motor protein; and (iii) creating a residing synthetic mobile from lifeless molecules. Dekker can be an elected member of the KNAW and fellow to the APS and the IOP.
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The biophysicist from Delft – who has become The most cited researchers within the Netherlands for years – takes his obligation to lead for the explanation and popularisation of his work within the border of physics and biology particularly severely and routinely appears during the media; Otherwise to mention his function, then about the connection involving science and his Christian faith.